NEM BannerAugust 20, 2014 (Carthage, MO USA) – Stratum Nutrition and ESM Technologies, partners in specialty health ingredients, are pleased to announce a new independent clinical trial has published in the Journal of Arthritis evaluating the joint health ingredient NEM® brand eggshell membrane.

An independent, multi-center clinical trial conducted in Germany by Weber & Weber GmbH and Co. KG confirmed the rapid reduction in pain found with NEM® brand eggshell membrane as in prior clinical trials.  The six-center study recruited 44 subjects with moderate, persistent knee and/or hip osteoarthritis.  The study participants were supplemented once daily with a capsule containing 500 mg of NEM® for 60 days and were evaluated at 10, 30, & 60 days using a short-form questionnaire based upon the WOMAC questionnaire.  The researchers found statistically significant reductions in pain as early as 10 days, with nearly one-quarter of the participants feeling at least a 30% improvement in this short time.  The improvement continued to the end of the study with more than 59% of the participants rating NEM’s efficacy as good or very good.  There were no serious adverse events in the study and NEM® was reported to be well tolerated.  The researchers concluded that this trial validates the clinical results seen with NEM® previously and that NEM® provides a viable natural treatment option for osteoarthritis of the knee or hip for the broader European population.  The results of the peer-reviewed study were recently published online in the Journal of Arthritis (doi:10.4172/2167-7921.1000136).

“We’re always pleased when an independent study is conducted that corroborates our own clinical results, particularly when it confirms NEM’s fast onset of efficacy.  The German researchers did an excellent job of validating NEM’s safety & efficacy, as well as patient acceptance, in a European population.” commented Kevin J. Ruff Ph.D., MBA, CCRP – Director of Scientific & Regulatory Affairs for ESM Technologies.

For more information on this new published data, please contact Dr. Kevin Ruff at


About ESM Technologies and Stratum Nutrition Joint Venture

ESM Technologies is the manufacturer of eggshell calcium and eggshell membrane wellness ingredients: ESC® and NEM®.  Located in Carthage, Missouri, the company researches, develops and manufactures high-quality branded ingredients from a traceable and sustainable supply of eggshells from USDA-inspected facilities. ESM is an NSF GMP certified facility that uses a chemical-free, patented process that allows the introduction of innovative and unique ingredients to the marketplace.  NEM® received the 2011 Frost & Sullivan North American Dietary Supplements for Joint Health New Product Innovation of the Year Award.

ESM Technologies and Stratum Nutrition formed a joint venture in 2011, allowing both companies to accelerate growth opportunities internationally. The companies work collaboratively to advance the science behind Stratum and ESM’s unique ingredients.  Together, ESM and Stratum capitalize on the strengths of both companies to further new product development and global sales of their combined specialty health ingredients portfolio for manufacturers and marketers of dietary supplements.

For more information on ESM Technologies, please visit or call 866.804.8034.

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